Application bulletins
Compaction simulators are a key technology allowing scientists to develop formulations and troubleshoot tablet defects. It means that formulation scientists or tech transfer engineers can assess the influence of process parameters on tablet properties to preempt
risk during scale-up or to solve production issues
with minimal powder consumption and avoiding
unnecessary use of production assets.
The goal of this study is to generate tablet defects
such as capping and use precompression to lessen
this phenomenon without modifying the formulation.
This will demonstrate that such tablet defects can
be foreseen on compaction simulators right from
the development stage to reduce cost and save time
during scale-up and production.
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