Formulation development and compaction of itraconazole amorphous solid dispersions tablets using quality by design principles
first_published_at:Jan. 2, 2023, midnight / date_published:Jan. 2, 2023
Bulletins
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02/01/2023 -
by
Hetvi Triboandas,
Mariana Bezerra,
Walkiria Schlindwein
Itraconazole (ITZ), a BCS Class II drug exhibiting low solubility (1-4 ng/mL in water) requires formulation enhancement to achieve enhanced bioavailability. To tackle this problem amorphous solid dispersions (ASDS) of …
