Further enhancement of the sustained-release properties and stability of direct compression gel matrix bilayer tablets by controlling the particle size of HPMC and drug microencapsulation
first_published_at:Sept. 6, 2024, midnight / date_published:Sept. 6, 2024
Papers
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06/09/2024 -
by
Tong Liu,
Jiahui Wang,
Yupeng Feng,
Haoran Wang,
Yunlong Xu,
Tian Yin,
Yu Zhang,
Haibing He,
Jingxin Gou,
Xing Tang
The Theophylline and Salbutamol Bilayer Sustained-release Tablets (Yi Xi Qing®), produced using wet granulation, are prone to discoloration during long-term storage, and the manufacturing process is less consistent and more …