Impact of moisture and magnesium stearate functionality on manufacturability of wet granulated metformin tablets
first_published_at:Aug. 18, 2017, midnight / date_published:Aug. 18, 2017
Papers
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18/08/2017 -
by
Umesh Kestur,
Divyakant Desai,
Shasad Sharif,
Benjamin Wong,
Hang Guo,
Dan Tang,
Steven Chan
Throughout the development of an 850 mg metformin hydrochloride tablet formulation using wet granulation, the tablets consistently displayed elevated friability levels (>3% w/w) regardless of the origin of extra-granular …
