A mechanistic understanding of compression damage to the dissolubility of coated pellets in tablets
first_published_at:Jan. 1, 2020, midnight / date_published:Jan. 1, 2020
Papers
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01/01/2020 -
by
Tze Ning Hiew,
Yu Harn Tian,
Huei Ming Tan,
Paul Wan Sia Heng
The potential harm to the drug diffusion coat barrier of controlled-release pellets due to compaction force during the preparation of multiple-unit pellet system tablets is a significant concern. Prior research …