Compression of vectors for small interfering RNAs delivery: toward oral administration of siRNA lipoplexes in tablet forms
first_published_at:April 6, 2020, midnight / date_published:April 6, 2020
Papers
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06/04/2020 -
by
Virginie Busignies,
Danielle Campiol Arruda,
Christine Charrueau,
Marcela Coelho Silva Ribeiro,
Anne-Marie Lachagès,
Angelo Malachias,
Stéphanie Finet,
Asad Ur Rehman,
Pascal Bigey,
Pierre Tchoreloff,
Virginie Escriou
Presently, the majority of nonviral nucleic acid vectors are formulated as colloidal suspensions primarily administered parenterally. This formulation and administration method impose significant constraints, such as vector size limitations and …
