Simultaneously improving tabletability and solubility of diclofenac by cocrystallization with picolinamide
first_published_at:Jan. 4, 2025, midnight / date_published:Jan. 4, 2025
Papers
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04/01/2025 -
by
Chenyu Wu,
Zijian Wang,
Xu Han,
Xinyi Yu,
Changquan Calvin Sun,
Zhengzheng Zhou
Diclofenac (DIC), a nonsteroidal anti-inflammatory drug, is characterized by poor tabletability and low water solubility. This study introduces a novel diclofenac-picolinamide cocrystal (DIC-PIC) aimed at improving both properties. The cocrystal …
