Influence of dissolution media pH and USP1 basket speed on erosion and disintegration characteristics of immediate release metformin hydrochloride tablets
first_published_at:July 4, 2015, midnight / date_published:July 4, 2015
Papers
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04/07/2015 -
by
Divyakant Desai,
Benjamin Wong,
Yande Huang,
Dan Tang,
Jeffrey Hemenway,
Srinivasa Paruchuri,
Hang Guo,
Daniel Hsieh,
Peter Timmins
Objective: Investigate the impact of dissolution medium pH on the immediate release of 850 mg metformin hydrochloride tablets.
Methods: Metformin hydrochloride tablets were manufactured using a conventional wet granulation method, …
