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Tableting Performance of Maize and Potato Starches Used in Combination as Binder/Disintegrant in Metronidazole Tablet Formulation

Tableting performance of maize and potato starches used in combination as binder/disintegrant in Metronidazole tablet formulation

Papers - 01/10/2022 - by Yonni Eshovo Apeji, Rejoice Thomas Kaigama, Sani Hadi Ibrahim, Sophie Nock Anyebe, Aisha Ohunene Abdussalam, Avosuahi Rukayat Oyi
The objective of this study was to evaluate the tableting characteristics of maize and potato starches when employed either as disintegrants or binders in the development of solid dosage forms. …
Tablet disintegration and dispersion under in vivo-like hydrodynamic conditions

Tablet disintegration and dispersion under in vivo-like hydrodynamic conditions

Papers - 16/01/2022 - by Jan Lenz, Frederik Fuest, Jan Henrik Finke, Heike Bunjes, Arno Kwade, Michael Juhnke
Disintegration and dispersion are crucial functional properties of tablets, playing a key role in achieving the desired release of the active pharmaceutical ingredient (API). The standard disintegration test (SDT), as …
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Influence of formulation parameters on tablet surface properties and film coating adhesion

Papers - 01/08/2020 - by Martin Wewers, Gernot Warnke, Jan Henrik Finke
Film coatings on tablets are commonly used to confer specific properties, such as achieving particular drug release profiles. The surface characteristics of tablet cores play a crucial role in the …
Characterisation of water uptake and swelling force of pharmaceutical tablets

Characterisation of water uptake and swelling force of pharmaceutical tablets

Papers - 25/09/2019 - by Daniel Puckhaber, Jan Henrik Finke, Lennart Lange, Michael Juhnke, Edgar John, Arno Kwade, Universitätsbibliothek Braunschweig
Tablets represent the predominant dosage form in the pharmaceutical industry, ensuring rapid drug release through quick tablet disintegration facilitated by the absorption of water into the tablet. As a result, …
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Chitin’s functionality as a novel disintegrant: benchmarking against commonly used disintegrants in different physicochemical environments

Papers - 01/07/2017 - by Mohammad Chaheen, Ian Soulairol, Bernard Bataille, Ahmad Yassine, Emmanuel Belamie, Tahmer Sharkawi
Disintegrants serve as excipients to facilitate the rapid disintegration of pharmaceutical tablets, ensuring proper dissolution of the active pharmaceutical ingredient. This study explores the disintegration mechanisms of chitin and common …