Switch of tablet manufacturing from high shear granulation to twin-screw granulation using quality by design approach
first_published_at:April 1, 2020, midnight / date_published:April 1, 2020
Papers
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01/04/2020 -
by
Yuta Miyazaki,
Vincent Lenhart,
Peter Kleinebudde
The objective of this study was to transition from a high shear granulation (HSG) process to a twin-screw granulation (TSG) process while ensuring comparable dissolution profiles. Ibuprofen (IBP) was utilized …
