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    Tablet ejection: A systematic comparison between force, static friction, and kinetic friction

    Tablet ejection: A systematic comparison between force, static friction, and kinetic friction

    Papers - 15/08/2024 - by Dingeman L.H. Van Der Haven, René Jensen, Maria Mikoroni, Umair Zafar, James A. Elliott, Ioannis S. Fragkopoulos
    The magnitude of frictional forces during the ejection of porous pharmaceutical tablets is crucial in determining the likelihood of tabletting defects. In this study, we conduct a systematic comparison of …
    Webinar_Measuring static & kinetic friction_Starting slide

    Measuring static and kinetic friction in routine compaction cycles and their implication for formulation development

    Webinar Replays - 05/07/2024 - by Danny van der Haven, Quentin Boulay
    The ejection of pharmaceutical tablets from the die is a critical moment after compaction during which defects can be induced if frictional forces are too high. Various studies have looked …
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    Influence of the punch speed on the die wall/powder kinematic friction during tableting

    Papers - 01/10/2019 - by Léo Desbois, Pierre Tchoreloff, Vincent Mazel
    Investigating the impact of compaction speed on the final tablet properties poses a significant challenge during the scale-up of solid dosage forms. While strain rate sensitivity is typically attributed to …
    Effect of friction between powder and tooling on the die-wall pressure evolution during tableting: Experimental and numerical results for flat and concave punches

    Effect of friction between powder and tooling on the die-wall pressure evolution during tableting: Experimental and numerical results for flat and concave punches

    Papers - 01/01/2019 - by V. Mazel, H. Diarra, P. Tchoreloff
    The final properties of tablets are predominantly determined during the compaction process by the development of stresses applied to the powder. Any parameter related to the process or product that …