The effect of HPMC particle size on the drug release rate and the percolation threshold in extended-release mini-tablets
first_published_at:Jan. 2, 2015, midnight / date_published:Jan. 2, 2015
Papers
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02/01/2015 -
by
Faiezah A. A. Mohamed,
Matthew Roberts,
Linda Seton,
James L. Ford,
Marina Levina,
Ali R. Rajabi-Siahboomi
The particle size of HPMC plays a crucial role in influencing the drug release rate from hydrophilic matrix systems. Percolation theory, a statistical tool, is employed to analyze the disorder …