The effects of spray drying, HPMCAS grade, and compression speed on the compaction properties of itraconazole-HPMCAS spray dried dispersions
first_published_at:Sept. 16, 2020, midnight / date_published:Sept. 16, 2020
Papers
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16/09/2020 -
by
Moshe Honick,
Sharmila Das,
Stephen W. Hoag,
Francis X. Muller,
Alaadin Alayoubi,
Xin Feng,
Ahmed Zidan,
Muhammad Ashraf,
James E. Polli
Spray-dried dispersions (SDDs) hold considerable potential in enhancing the oral bioavailability of drugs with limited water solubility. Nevertheless, SDDs often exhibit material attributes, such as small particle size, low bulk …
