Salcaprozate-based ionic liquids for GLP-1 gastric delivery: A mechanistic understanding of in vivo performance
first_published_at:Jan. 10, 2025, midnight / date_published:Jan. 10, 2025
Papers
-
10/01/2025 -
by
René Rebollo,
Zhigao Niu,
Lasse Blaabjerg,
Damiano La Zara,
Trine Juel,
Henrik Duelund Pedersen,
Vincent Andersson,
Michaela Benova,
Camilla Krogh,
Raphaël Pons,
Tobias Palle Holm,
Per-Olof Wahlund,
Li Fan,
Zhuoran Wang,
Adam Kennedy,
Rune Ehrenreich Kuhre,
Philip Christophersen,
Pierre-Louis Bardonnet,
Philip Jonas Sassene
Peptide delivery through oral formulations requires high concentrations of permeation enhancers (PE) to facilitate absorption and often involves fasting between dosing and food intake. Developing formulations that enable rapid absorption …
