Production of extended release mini-tablets using directly compressible grades of HPMC
first_published_at:Nov. 1, 2013, midnight / date_published:Nov. 1, 2013
Papers
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01/11/2013 -
by
Faiezah A. A. Mohamed,
Matthew Roberts,
Linda Seton,
James L. Ford,
Marina Levina,
Ali R. Rajabi-Siahboomi
Background: Hypromellose (HPMC) has been utilized previously to regulate drug release in mini-tablets. However, due to suboptimal flow characteristics, the production of mini-tablets with elevated HPMC levels presents a challenge. …