Understanding the role of magnesium stearate in lowering punch sticking propensity of drugs during compression
first_published_at:May 6, 2023, midnight / date_published:May 6, 2023
Papers
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06/05/2023 -
by
Chamara A. Gunawardana,
Angela Kong,
Debbie Wanapun,
Daniel O. Blackwood,
C. Travis Powell,
Joseph F. Krzyzaniak,
Myles C. Thomas,
John E. Kresevic,
Changquan Calvin Sun
The adherence of active pharmaceutical ingredient (API) to compaction tooling surfaces, commonly known as punch sticking, can lead to costly downtime or product failures during commercial tablet manufacturing. Magnesium stearate …