Efficient development of sorafenib tablets with improved oral bioavailability enabled by coprecipitated amorphous solid dispersion
first_published_at:Dec. 15, 2021, midnight / date_published:Dec. 15, 2021
Papers
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15/12/2021 -
by
Sichen Song,
Chenguang Wang,
Shan Wang,
Ronald A. Siegel,
Changquan Calvin Sun
A hydroxypropyl methylcellulose acetate succinate (HPMC-AS) amorphous solid dispersion (ASD) of sorafenib (SOR), prepared through coprecipitation, was utilized for the development of an immediate release tablet with enhanced oral bioavailability. …
