Tablet disintegratability: sensitivity of superdisintegrants to temperature and compaction pressure
first_published_at:Dec. 6, 2022, midnight / date_published:Dec. 6, 2022
Papers
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06/12/2022 -
by
Audrey Yi Zheng,
Paul Wan Sia Heng,
Lai Wah Chan
Tablet disintegration is a crucial prerequisite for drug dissolution and absorption. While the disintegration test conventionally takes place at 37 °C, intragastric temperature variations can occur due to meals or …