Modeling of disintegration and dissolution behavior of mefenamic acid formulation using numeric solution of Noyes-Whitney equation with cellular automata on microtomographic and algorithmically generated surfaces
first_published_at:Dec. 3, 2018, midnight / date_published:Dec. 3, 2018
Papers
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03/12/2018 -
by
Reiji Yokoyama,
Go Kimura,
Christian Schlepütz,
Jörg Huwyler,
Maxim Puchkov
Manufacturing parameters can significantly influence the dissolution and disintegration of solid dosage forms. In alignment with Process Analytical Technology (PAT) and Quality by Design (QbD) approaches, computer-based technologies offer the …
