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760 results

6 results

Date

Evaluation of the effect of granule size of raw tableting materials on critical quality attributes of tablets during the continuous tablet manufacturing process using near-infrared spectroscopy
in Papers - Makoto Otsuka, Tokiro Ogata, Yusuke Hattori, Tetsuo Sasaki.
The impact of granule size variation in raw materials on tablet hardness (TH) and weight (TW) within the continuous tabl...
The ubiquity of the tabletability flip phenomenon
in Papers - Zijian Wang, Chenguang Wang, Deepak Bahl, Changquan Calvin Sun.
The malleability of materials plays a crucial role in achieving effective powder tabletability, a key factor in the deve...
Choosing the correct tool material specification
in White papers - 14/12/2023 - n/a
Michael Oxford, Research and Design Engineer at I Holland explains how I Holland recently helped pharma group Accord Hea...
Consolidation of spray-dried amorphous Calcium Phosphate by ultrafast compression: chemical and structural overview
in Papers - Sylvain Le Grill, Christophe Drouet, Olivier Marsan, Yannick Coppel, Vincent Mazel, Marie-Claire Barthelemy, Fabien Brouillet.
A significant portion of research within the orthopedic and maxillofacial fields is devoted to advancing bioactive 3D sc...
Improving active pharmaceutical ingredient formulation by hot melt extrusion
in Newsfeeds - 10/06/2024 - n/a
This poster, presented at the PBP World Meeting 2024 in Vienna, explores the integration of AI and big data in pharmaceu...
Tooling terminology
in Bulletins - none
All what you need to know about the size & format of Punches & Dies. Some terminology such as D, B, 441, EU, TSM...
Processing challenges with solid dosage formulations containing vitamin E TPGS
in Papers - Preetanshu Pandey, Patrick D. Sinko, Dilbir S. Bindra, Rhye Hamey, Shruti Gour, Chandra Vema-Varapu.
This study aims to explore the challenges associated with incorporating Vitamin E TPGS (d-α tocopheryl polyethylene glyc...
A combined experimental and modeling approach to study the effects of high-shear wet granulation process parameters on granule characteristics
in Papers - Preetanshu Pandey, Jing Tao, Anwesha Chaudhury, Rohit Ramachandran, Julia Z. Gao, Dilbir S. Bindra.
The current study aims to investigate the impact of high-shear wet granulation process parameters on granule characteris...
The role of continuous manufacturing in large-batch production
in Newsfeeds - 25/03/2024 - n/a
The text discusses the potential of Continuous Manufacturing as a production organization for pharmaceuticals, particula...
Ebook: Twin-screw extrusion for pharmaceutical applications
in Newsfeeds - 03/07/2024 - n/a
This compendium provides a comprehensive guide on how hot-melt extrusion (HME) can address common challenges in pharmace...
Influence of layer composition and compaction parameters on the manufacturing of sucralfate/ibuprofen lysine bi-layer tablets
in Papers - Alessandra Rossi, Matteo Molinari, Fabiola Lombardi, Luca Castrati, Dimitrios Rekkas, Stavros Politis, Ruggero Bettini, Paolo Colombo.
Investigation into the impact of layer composition and compaction parameters on the tendency of delamination in bi-layer...
A powder tabletability equation
in Posters - Gerrit Vreeman, Changquan Calvin Sun.
A mathematical expression delineating the relationship between the tensile strength of tablets and compaction pressure w...

pTab – A personalized bilayer tablet

first_published_at:June 10, 2025, midnight / date_published:June 10, 2025

Papers - 10/06/2025 - by Florian Tiltscher, Friederike Gütter, Monika Buchholz, Sebastian Eichler, Pierre Braun, Moritz Rosch

Standardized doses in tablets are suitable for most APIs and patient groups. However, there are many instances in which personalized medication enables huge benefits for the patients. Especially if the …

MEDELPHARM's participation at AAPS PharmSci 360 2024: Innovations in tablet formulation

first_published_at:Oct. 30, 2024, 4:06 p.m. / date_published:None

Newsfeeds - 30/10/2024 - by Gabrielle Dupont

At the recent AAPS PharmSci 360, held from October 20th-23rd, 2024, in Salt Lake City, MEDELPHARM showcased its latest advancements in tablet formulation technology alongside KORSCH America. This collaboration featured …

Webinar KIN 2 - Multilayer - Thumbnail slide

Webinar series India - Multilayer tablets: from R&D formulation development to production scale-up

first_published_at:June 5, 2024, 9:44 a.m. / date_published:March 2, 2023

Webinar Replays - 05/06/2024 - by Quentin Boulay, Bruno Leclercq, Pavan Porethi, Pravin Gawas

Multilayer tablets are often the best solution to combine more than one API into a single dosage form. The main advantage is that the API contained in each layer of …

Bilayer tablet manufacturing - An overview

first_published_at:March 8, 2024, 2:58 p.m. / date_published:None

Newsfeeds - 08/03/2024 -

The text highlights the advantages and challenges of bilayer tablets in pharmaceutical formulations. Bilayer tablets offer controlled delivery of one or more active pharmaceutical ingredients (APIs) within a single tablet, …

Effect of the curvature of the punches on the shape of the interface and the delamination tendency of bilayer tablets

first_published_at:May 1, 2017, midnight / date_published:May 1, 2017

Papers - 01/05/2017 - by Luca Castrati, Vincent Mazel, Harona Diarra, Virginie Busignies, Pierre Tchoreloff

Bilayer tablets hold special significance in the pharmaceutical industry, and a primary challenge in their manufacturing is the occurrence of delamination during or after ejection from the die. This study …

Comparison of breaking tests for the characterization of the interfacial strength of bilayer tablets

first_published_at:Nov. 1, 2016, midnight / date_published:Nov. 1, 2016

Papers - 01/11/2016 - by Luca Castrati, Vincent Mazel, Virginie Busignies, Harona Diarra, Alessandra Rossi, Paolo Colombo, Pierre Tchoreloff

The adoption of bilayer tableting technology is increasing in the pharmaceutical industry due to its effectiveness in enhancing drug delivery strategies. The European Pharmacopoeia currently suggests evaluating the mechanical strength …

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Evaluation of the effect of granule size of raw tableting materials on critical quality attributes of tablets during the continuous tablet manufacturing process using near-infrared spectroscopy

The ubiquity of the tabletability flip phenomenon

Choosing the correct tool material specification

Consolidation of spray-dried amorphous Calcium Phosphate by ultrafast compression: chemical and structural overview

Improving active pharmaceutical ingredient formulation by hot melt extrusion

Tooling terminology

Processing challenges with solid dosage formulations containing vitamin E TPGS

A combined experimental and modeling approach to study the effects of high-shear wet granulation process parameters on granule characteristics

The role of continuous manufacturing in large-batch production

Ebook: Twin-screw extrusion for pharmaceutical applications

Influence of layer composition and compaction parameters on the manufacturing of sucralfate/ibuprofen lysine bi-layer tablets

A powder tabletability equation

pTab – A personalized bilayer tablet

MEDELPHARM's participation at AAPS PharmSci 360 2024: Innovations in tablet formulation

Webinar series India - Multilayer tablets: from R&D formulation development to production scale-up

Bilayer tablet manufacturing - An overview

Effect of the curvature of the punches on the shape of the interface and the delamination tendency of bilayer tablets

Comparison of breaking tests for the characterization of the interfacial strength of bilayer tablets