An effort to enhance the clinical translatability of caprate-based tablet formulations in gastric peptide delivery
first_published_at:Sept. 23, 2025, midnight / date_published:Sept. 23, 2025
Papers
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23/09/2025 -
by
Pierre-Louis Bardonnet,
Zhigao Niu,
Jenni Pessi,
Maria Kazakou,
Konstantinos Raptis,
Reece McCabe,
Anders Toftlev,
René Rebollo,
Zhuoran Wang,
Li Fan,
Nicolai Rytter Mortensen,
Lars Bardtrum,
Vincent Andersson,
Per-Olof Wahlund,
Mathias Norrman,
Andrew James Benie,
Jian Xiong Wu,
Max Sauter,
Damiano La Zara,
Philip Christophersen,
Philip Jonas Sassene
Sodium caprate (C10) is one of the most extensively studied permeation enhancers for improving oral peptide uptake. Yet, its effectiveness in clinical settings may be compromised by the acidic environment …
