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NEWSFEEDS

Trends in solid dosage forms and their challenges for R&D and manufacture

April 24, 2024
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CI Precision discusses the importance of innovation in the pharmaceutical industry, focusing on advancements in drug delivery and targeting systems. It highlights the significance of solid dosage forms beyond active ingredients, emphasizing improvements in efficacy, patient experience, and commercial differentiation. Various challenges in research, production, and quality control are addressed, particularly in working with new dosage forms.

The demand for alternative solid dosage forms is growing, driven by consumer choice, patient compliance, and technical advancements. Examples include orodispersible tablets, implantable dosages, digitally integrated devices, and 3D printing. However, manufacturing these new forms presents challenges such as non-standard shapes, stickiness, formulation adjustments, and the need for controlled environments.

Ensuring conformance and patient safety is crucial, with regulators emphasizing data-driven processes and precision weighing for compliance and commercial reasons. Overall, the pharmaceutical industry must adapt to these innovations by rethinking processes and machinery to meet the demands of modern drug delivery systems.

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