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    A STICKY ISSUE- TRANSFORMING OILY PLANT EXTRACTS INTO SOLID ORAL DOSAGE FORMS - image

    A sticky issue: transforming oily plant extracts into solid oral dosage forms

    Newsfeed - 21/10/2025 -
    The article explores the challenges of converting oily or sticky plant extracts into solid oral dosage forms, such as tablets. Due to their natural properties, these extracts can be difficult …
    API active pharmaceutical ingredient

    Effervescent tablet preparation by twin-screw melt granulation

    Newsfeed - 15/10/2025 -
    In a recent study, effervescent granules containing citric acid and sodium bicarbonate were successfully prepared using twin-screw melt granulation (TS-MG) with sorbitol as a melt binder. This approach offers a …
    Image - How to select the ideal HPAPI manufacturing partner

    Strategies for successful manufacturing of highly potent oral solids

    Newsfeed - 14/10/2025 -
    Highly potent active pharmaceutical ingredients (HPAPIs) are increasingly prominent in drug development, but their poor solubility and low bioavailability present formulation challenges. To address these issues, manufacturers use enabling technologies …
    Big batch of tablets

    Pilot plant prep

    Newsfeed - 09/10/2025 -
    In the article "Pilot Plant Prep" from Nutritional Outlook, Fred Murray, President of KORSCH America, emphasizes the critical importance of aligning pilot-scale tablet presses with full-scale production machines. He warns …
    advances in oral delivery of protein and peptide drugs - image

    Advances in the oral delivery of protein and peptide drugs

    Newsfeed - 08/10/2025 -
    The article "Advances in the Oral Delivery of Protein and Peptide Drugs" from Pharma Excipients discusses the significant challenges and recent innovations in formulating oral dosage forms for protein and …
    Compaction simulators - STYL'One Nano-s

    STYL'One University Contest: Winners announced!

    Newsfeed - 07/10/2025 -
    The STYL’One University Contest, launched last February by MEDELPHARM and KORSCH, has officially reached its conclusion. This first edition invited universities from around the world to submit innovative projects in …
    High-Loaded Dosage Forms - image

    High-loaded dosage forms

    Newsfeed - 06/10/2025 -
    The article "High-Loaded Dosage Forms: Novel Platform Expands Dispersion Utility" presents advancements in developing high drug-loaded amorphous solid dispersions (ASDs) to improve the bioavailability of poorly soluble compounds. Traditional ASD …
    Merck formulation handbook - image

    Formulation handbook from Merck

    Newsfeed - 02/10/2025 -
    Formulating the perfect dosage form is no easy task. With so many techniques and excipients available, every decision made during development can influence the performance and success of the final …
    API active pharmaceutical ingredient

    Poor API quality threatens a healthy supply

    Newsfeed - 30/09/2025 -
    Poor API quality—from low potency, uncontrolled impurities, or batch-to-batch variability—can undermine drug efficacy and safety, shorten shelf life, and lead to production delays, drug shortages, or recalls that disrupt the …
    Capture Virtual Pharma Expo

    Predictive tablet press scale-up from R&D to production with STYL’One Evo Compaction Simulator

    Newsfeed - 26/09/2025 -
    At the Virtual Pharma Expo 2025, KORSCH America showcased the STYL’One Evo Compaction Simulator, a cutting-edge solution that helps pharmaceutical formulators predict high-speed tablet performance and accelerate scale-up from lab …
    high-angle-view-white-medical-tablets

    Strategies for successful manufacturing of highly potent oral solids

    Newsfeed - 26/09/2025 -
    The article discusses essential strategies for manufacturing highly potent oral solids (HPAPIs) and offers guidance for sponsors evaluating Contract Development and Manufacturing Organizations (CDMOs). It emphasizes stringent containment and safety …
    Dry granulation in solid oral formulation- advantages of spray-dried mannitol - image

    Dry granulation in solid oral formulation: advantages of spray-dried mannitol in roll compaction

    Newsfeed - 25/09/2025 -
    The article explores the benefits of spray-dried mannitol as a filler/binder in dry granulation via roller compaction, a technique particularly suited to moisture- and heat-sensitive APIs since it avoids wet …