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    pilules-bocal-verre

    Modified Release Formulations: Extending Drug Commercial Lifecycle

    Newsfeeds - 30/04/2024 -
    The text discusses the evolving landscape of drug release systems, emphasizing the shift from immediate release formulations to modified dosage forms. These modifications aim to enhance patient compliance, achieve therapeutic …
    pilules-blanches-tombent-bouteille

    Manufacturing Equipment Trends

    Newsfeeds - 30/04/2024 -
    The text provides an overview of pharmaceutical and biopharmaceutical manufacturing processes, emphasizing the need for flexibility, containment, and operating efficiency in equipment. It discusses trends in the industry such as …
    pilules-bocal-verre

    The Benefits Of Using GenAI In Drug Discovery And Preclinical Development

    Newsfeeds - 26/04/2024 -
    The article discusses the potential benefits of utilizing generative artificial intelligence (GenAI) in drug discovery and preclinical development. It emphasizes how GenAI can reform the drug discovery process by creating …
    Image Trends in solid dosage forms - weight sorting

    Trends in solid dosage forms and their challenges for R&D and manufacture

    Newsfeeds - 24/04/2024 -
    CI Precision discusses the importance of innovation in the pharmaceutical industry, focusing on advancements in drug delivery and targeting systems. It highlights the significance of solid dosage forms beyond active …
    _DSC2084 copie

    MEDELPHARM bringing expertise in research and development at Compaction Simulation Forum in Dublin

    Newsfeeds - 22/04/2024 -
    MEDELPHARM, a leading name in pharmaceutical equipment and technology, is getting ready to participate at the upcoming Compaction Simulation Forum (CSF), scheduled to take place from June 4th to 6th …
    Image - Why are pharma companies reluctant cloud

    Why Are Pharmaceutical Companies Reluctant to Adopt Cloud Technologies

    Newsfeeds - 22/04/2024 -
    The Cloud Industry Forum's 2023 report indicates that the majority of businesses across various sectors have adopted cloud technology, with 55% utilizing a hybrid approach and 42% embracing a cloud-first …
    Image - Choosing the optimal dosage form for your moleculex600

    Choosing the optimal dosage form for your molecule

    Newsfeeds - 22/04/2024 -
    There are many factors to consider when choosing the right oral dosage form for your active pharmaceutical ingredient (API) leading up to clinical trials, including:- Drug profile- Ease of formulation …
    pilules-bocal-verre

    Emerging Trends And Challenges For Pharmaceutical Production

    Newsfeeds - 15/04/2024 -
    The global pharmaceutical market, valued at around 1.25 trillion USD, is expected to grow steadily, with the United States leading in revenue generation. Despite the COVID-19 pandemic, pharmaceutical supply chains …
    Image Fabrication and Optimization of Directly Compressible Self-Emulsifying Tablets Containing Cannabis Extract Obtained from Supercritical Carbon Dioxide Extraction

    Fabrication and Optimization of Directly Compressible Self-Emulsifying Tablets Containing Cannabis Extract Obtained from Supercritical Carbon Dioxide Extraction

    Newsfeeds - 15/04/2024 -
    The text discusses the challenges of low bioavailability of Tetrahydrocannabinol (THC) and Cannabidiol (CBD) in orally administered cannabis extract due to first-pass metabolism. It explores the use of a self-emulsifying …
    Nano_on_table_transparent

    AustinPx Invests in Pharmaceutics and Manufacturing Capabilities to Accelerate Drug Development

    Newsfeeds - 11/04/2024 -
    AustinPx, a prominent contract development and manufacturing organization (CDMO) focusing on enhancing the bioavailability of orally delivered small molecule drug candidates, has announced the acquisition of cutting-edge equipment to bolster …
    Image Hot-Melt extrusion - from theory to application in pharmaceutical formulation - where are we now

    Hot-Melt Extrusion: from Theory to Application in Pharmaceutical Formulation – Where Are We Now?

    Newsfeeds - 10/04/2024 -
    Hot-melt extrusion (HME) stands as a widely acknowledged and robust technology, effectively enhancing the bioavailability of poorly soluble active pharmaceutical ingredients while offering an efficient continuous manufacturing process. The twin-screw …
    Image Right from the start Designing advanceable formulations and processes at phase 1

    Right from the start: Designing Advanceable Formulations and Processes at Phase I

    Newsfeeds - 09/04/2024 -
    The text discusses the importance of designing drug formulations and processes that are advanceable from the early stages of development, emphasizing safety, efficacy, manufacturability, and commercial viability. It highlights the …
    Image Rapid And Material-Sparing Feasibility Screening For Hot Melt Extrusion

    Rapid And Material-Sparing Feasibility Screening For Hot Melt Extrusion

    Newsfeeds - 05/04/2024 -
    Amorphous solid dispersions (ASD) present a solution for enhancing the bioavailability of crystalline APIs that are otherwise poorly soluble. Two primary methods for manufacturing ASDs are spray drying and hot …
    Illustration article Interphex

    KORSCH America highlights latest tableting technology during Interphex 2024

    Newsfeeds - 03/04/2024 -
    KORSCH America Inc., division of KORSCH AG., a leading name in the pharmaceutical equipment manufacturing industry, is preparing its participation at Interphex in New York. Scheduled from April 16th to …
    Image KORSCH X 5 Contract Pharma

    KORSCH to Introduce Advanced X 5 Tablet Press at INTERPHEX

    Newsfeeds - 02/04/2024 -
    KORSCH America, the U.S. subsidiary of KORSCH AG, will unveil its latest tablet press, the X 5, at INTERPHEX in New York City. This innovative single-sided rotary press offers increased …
    Image Impact testing as a new approach to determine mechanical strength of pharmaceutical tablets

    Impact testing as a new approach to determine mechanical strength of pharmaceutical tablets

    Newsfeeds - 02/04/2024 -
    The paper discusses shortcomings in traditional standardized testing methods for determining tablet strength in the pharmaceutical industry, particularly focusing on the tablet breaking force test and friability test. These methods …
    Image Continuous production KORSCH LB Bohle

    The Role of Continuous Manufacturing in Large-Batch Production

    Newsfeeds - 25/03/2024 -
    The text discusses the potential of Continuous Manufacturing as a production organization for pharmaceuticals, particularly in high-volume production. Dr. Robin Meier, Chief Scientific Officer at L.B. Bohle, provides insights into …
    Galenic laboratory Armor - video screen

    See the Galenic Laboratory at Armor Pharma

    Newsfeeds - 15/03/2024 -
    Since 2020, Armor Pharma has made significant investments in a cutting-edge galenic laboratory, enhancing their expertise as a leading pharmaceutical lactose provider.Check out the latest video showcasing Armor Pharma's State-of-the-art …
    ODT tab iStock-451630933

    Is My Molecule Suitable for an Orally Disintegrating Tablet

    Newsfeeds - 13/03/2024 -
    Orally Disintegrating Tablets (ODTs) are a favored option for patients, providing added advantages in terms of delivering and absorbing the active pharmaceutical ingredient (API) before reaching the stomach. Incorporating ODT …
    Image Excipient-based strategies to harness complex therapeutics

    Excipient-based strategies to harness complex therapeutics

    Newsfeeds - 12/03/2024 -
    The article discusses the challenges associated with small molecule drugs in pharmaceutical formulations, particularly focusing on their poor water solubility. It highlights that a significant percentage of marketed drugs and …
    image twin screw granulation process

    A QbD Guided Development of a Twin-Screw Granulation Process

    Newsfeeds - 12/03/2024 -
    The text discusses dry granulation techniques in the pharmaceutical industry, focusing on roller compaction and slugging, highlighting their limitations such as inferior tablet strength and reduced yield due to fine …
    Bilayer tablet MEDELPHARM Vom hofe

    Bilayer tablet manufacturing - An overview

    Newsfeeds - 08/03/2024 -
    The text highlights the advantages and challenges of bilayer tablets in pharmaceutical formulations. Bilayer tablets offer controlled delivery of one or more active pharmaceutical ingredients (APIs) within a single tablet, …
    MEDELPHARM PBP World Meeting LinkedIn

    MEDELPHARM highlights innovative solutions at PBP World Meeting

    Newsfeeds - 06/03/2024 -
    MEDELPHARM, a leading provider of innovative solutions for pharmaceutical research and development, will be participating in the upcoming PBP World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology in Vienna from …
    image preformulation drug development

    Best Practices For Preformulation In Drug Development

    Newsfeeds - 05/03/2024 -
    The text discusses the importance and methodologies of preformulation testing in drug development, which involves studying new drug compounds to gather essential information for formulating stable and biopharmaceutically suitable dosage …
    Laboratory network - image - strategies to formulate poorly soluble api

    4 Strategies To Formulate Poorly Soluble APIs

    Newsfeeds - 01/03/2024 -
    The text discusses strategies employed by researchers and pharmaceutical scientists to address the challenge of poor solubility in APIs. It outlines four main techniques: lipid-based formulations, amorphous solid dispersions, nanotechnology, …
    White powder heap

    MEGGLE highlights role of excipient properties in alcohol-induced dose dumping AIDD

    Newsfeeds - 01/03/2024 -
    The white paper from MEGGLE emphasizes the significance of excipients in addressing alcohol-induced dose dumping (AIDD) in modified-release tablet formulations. AIDD occurs when drugs prematurely release into the bloodstream due …
    Tablet_Multilayer_15_HD.original

    Retrospective analysis of the biopharmaceutics characteristics of solid oral Modified-Release drug products

    Newsfeeds - 20/02/2024 -
    This retrospective study, spanning from 2001 to 2021, examined submissions approved by the US Food and Drug Administration (FDA) for Modified Release (MR) orally administered drugs [Extended-Release (ER) and Delayed-Release …
    Yellow tablets iStock-1218616175

    Flexible granulation

    Newsfeeds - 20/02/2024 -
    The process of pharmaceutical granulation plays a pivotal role in producing solid dosage forms, directly influencing the efficacy, stability, and overall quality of the drug. Within pharmaceutical manufacturing, flexible granulation …
    round-tablets-on-yellow-background-3683057

    PEARLITOL® 200 GT Mannitol: Harnessing the potential of higher active ingredient content for smaller, more convenient tablets

    Newsfeeds - 20/02/2024 -
    The article discusses the development and optimization of PEARLITOL® 200 GT, a new pure beta mannitol grade for direct compression in tablet manufacturing. Mannitol is commonly used as an excipient …
    Granutools - Granupack Permeability

    Granutools introduces the GranuPack permeability

    Newsfeeds - 06/02/2024 -
    Granutools has introduced the GranuPack Permeability Unit, a revolutionary device for analyzing powder permeability in various packing conditions. Essential for industries like pharmaceuticals, food production, and additive manufacturing, the unit …
    Tablet_TabInTab-vs-Multilayer_8_centered

    Modified-release formulation strategies

    Newsfeeds - 31/01/2024 -
    The increasing popularity of modified-release (MR) dosage forms is attributed to the numerous therapeutic advantages they provide for both drug developers and patients. Oral MR formulations are specifically designed to …
    KORSCH X 5

    New KORSCH X 5 advanced Single-Sided Tablet Press delivers major productivity gains

    Newsfeeds - 31/01/2024 -
    KORSCH AG has introduced the X 5 Tablet Press, an advanced single-sided rotary press that significantly enhances productivity in tablet manufacturing. Launched at Interpack 2023, the X 5 offers a …
    Image current trends and challenges influencing the oral solid dose market

    Current trends and challenges influencing the oral solid dose market

    Newsfeeds - 23/01/2024 -
    The article discusses current trends and challenges in the oral solid dose (OSD) market, focusing on the influence of patient-centric formulations and advancements in excipients. Key points include the importance …
    ThermoFisher - Solving for Solubility a scale-up strategy for spray-dried dispersions

    Solving for solubility: a scale-up strategy for spray dried dispersion

    Newsfeeds - 12/01/2024 -
    Webinar replay by ThermoFisherSpray drying provides a remedy for formulation obstacles in improving the bioavailability of poorly soluble APIs. While the procedure is thoroughly comprehended, achieving successful spray drying demands …
    cdmo industry INCOG

    3 key trends shaping the CDMO industry in 2024

    Newsfeeds - 12/01/2024 -
    The article discusses three key trends shaping the Contract Development and Manufacturing Organization (CDMO) industry in 2024 and beyond:* Transition Towards Customer-Driven Manufacturing (CdMO)- The biopharma industry is evolving, and …
    Image empowering the pharma workforce

    Empowering the pharma workforce

    Newsfeeds - 04/01/2024 -
    The pharmaceutical manufacturing industry is undergoing a significant transformation, facing challenges in workforce training, particularly due to rising costs and logistical issues. The emergence of generative AI (GenAI) is poised …
    Tablet_Multilayer_15_HD.original

    The effect of compression pressure on the first layer surface roughness and delamination of Metformin and Evogliptin bilayer and trilayer tablets

    Newsfeeds - 18/12/2023 -
    The study aimed to assess the delamination of convex-shaped tablets containing metformin HCl (MF) and evogliptin tartrate (EG) based on pre-compression and main compression pressures. Simultaneously, the study sought to …
    Lactalis Ingredients Pharma powder (from website)

    Development of pharmaceutical lactose by Lactalis Ingredients Pharma

    Newsfeeds - 12/12/2023 -
    Pharmaceutical grade lactose, used as binder or diluent, is a standard excipient for the formulation of Oral Solid Dose medicines. Versatile thanks to its various fabrication processes leading to different …
    illustration Exploring Best-Practice Manufacturing Strategies for Highly Potent Oral Solid Dosage Forms

    Exploring best-practice manufacturing strategies for highly potent oral solid dosage forms

    Newsfeeds - 23/11/2023 -
    Exploring key points for manufacturing Highly Potent Oral Solid Dosage Forms:*Challenges of Highly Potent Oral Solid Dose (HPOSD) Manufacturing:The increasing development and market presence of highly potent oral solid dose …
    Fig.-2-Tableting-study

    Tableting of liquid form active ingredient with high performance liquid carrier

    Newsfeeds - 07/11/2023 -
    The article discusses the use of FLORITE, a macro porous calcium silicate, as a practical alternative to liquid carriers for tableting formulations with liquid active ingredients.Fish oil was utilized as …
    reformulation by Biogrund

    The art of reformulation: tablet formulations redefined

    Newsfeeds - 06/11/2023 -
    The article discusses the significance of tablet reformulation in the pharmaceutical and dietary supplement industry. Reformulation is vital for improving efficacy, tolerability, and patent competitiveness. The process involves steps such …
    a qbd approach

    Technical considerations for developing oral solids

    Newsfeeds - 24/10/2023 -
    Part 1 of the series by Pfizer CentreOne focuses on technical considerations for developing oral solids. The article emphasizes the significance of thorough technical groundwork and understanding excipients during the …
    Medelpharm-Group of tablets

    How to achieve different release profiles and select excipients for formulation development of modified release oral solid dosage forms

    Newsfeeds - 24/10/2023 -
    The white paper by Societal CDMO takles the following key points:1 - Importance of modified release oral solid dosage forms in enabling prolonged or targeted drug delivery, leading to improved …
    white-medication-pill-on-blue-textile-3683079.width-1200

    Characterizing drug substance properties early can optimize drug development formulation

    Newsfeeds - 23/10/2023 -
    This article examines the following key points: 1 - Early drug substance (DS) characterization is crucial as changes in the DS process can affect the drug product (DP), including purity, …
    KORSCH Magazine- high-volume tablet production

    KORSCH Magazine - high-volume tablet production

    Newsfeeds - 23/10/2023 -
    KORSCH AG takes a closer look at the developments, trends and future prospects around high-volume tablet production for pharma and nutraceutical applications. In addition, KORSCH presents their new X 5 …
    1654153224212.original

    KORSCH Magazine - research & development, our customers respond

    Newsfeeds - 27/06/2022 -
    KORSCH AG conducted revealing interviews with customers on this magazine focused on Research and Development. It provides a detailed insight into the processes and challenges involved in successful product development, …
    Skyepharma tab-in-tab

    Tab-in-tab: Skyepharma and Université de Bordeaux share collaborative thesis

    Newsfeeds - 16/05/2022 - by Léo Picart
    To read, directly on the Skyepharma website, an update on a collaborative thesis on “Mechanical resistance of pharmaceutical press coated tablets (tab-in-tab): characterization and link with material and process parameters”.This …
    581208

    The expanding role of effervescent technology

    Newsfeeds - 08/04/2022 -
    This article explains the benefits and applications of effervescent technology in solid dosage forms from beverages to laundry detergent.
    Tablet_Multilayer_15_HD.original

    Exploring bilayer tablet manufacturing

    Newsfeeds - 01/12/2021 -
    Article published on Pharmaceutical Online that reviews selecting this specific dosage form, manufacturing challenges and how to overcome them, considerations for evaluating a CDMO, and the typical timeframe for scale-up.
    ME-S2-300-091

    What are advantages of external lubrication on a tablet press compared to folding lubrication into the blend?

    Newsfeeds - 07/10/2021 -
    Spotted across the web an efficient summary of the Pro's and Con's of adding MgSt directly into the product blend vs external lubrication.
    Orally-disintegrating-tablets-offer-range-of-patient-benefits

    Orally disintegrating tablets offer range of patient benefits: Roquette

    Newsfeeds - 24/08/2021 -
    A leader from the excipients firm discusses how ODTs appeal to seniors and patients on the go, and the formulation-related challenges with such tablets.
    first-impressions-tablet-shape-can-impact-2

    First impressions: tablet shape can impact patient acceptance

    Newsfeeds - 24/11/2020 -
    The article discusses the crucial role of tablet design in shaping consumer perception and acceptance, particularly in pharmaceutical, nutritional, and confectionary industries. It highlights the limitations of the flat faced …
    BRC_100_033 - L.B. Bohle

    Roller compaction: new trends, challenges and solutions

    Newsfeeds - 12/11/2020 -
    This article explains the 3 known technologies to develop tablets:- direct compression- wet granulation- dry granulation, with a focus on roller compaction, as it remains an effective solution for most …
    white-medication-pill-on-blue-textile-3683079.width-1200

    Are tablets still relevant?

    Newsfeeds - 17/07/2020 -
    CPI's Dave Berry explains the rising demand for tablets, and the trend towards continuous processing in the pharmaceutical industry. There is a need today for higher flexibility through modular physical …
    Orally-disintegrating-tablets-offer-range-of-patient-benefits

    List of excipients for direct compression

    Newsfeeds - 07/07/2020 -
    Pharma Excipients has released on their website a list of excipients that can be used for direct compression with the function/application and manufacturer. Binders, lubricants and disintegrants are an important …