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    spray-dried lubricants offering enhanced flowability - image

    Spray dried lubricants offering enhanced flowability

    Newsfeeds - 31/07/2025 -
    The article "Spray Dried Lubricants Offering Enhanced Flowability" discusses the development and evaluation of novel spray-dried lubricants designed to improve the flowability of tablet formulations, especially in continuous manufacturing processes.The …
    Impact of solid content on the bulk properties of lyophilized powders

    Impact of solid content on the bulk properties of lyophilized powders

    Papers - 10/02/2025 - by Zijian Wang, Sichen Song, Hongwei Zhang, Xiaohong Liu, Ronald A. Siegel, Changquan Calvin Sun, Chenguang Wang
    Interest in the oral delivery of biologics, often formulated via lyophilization, is growing rapidly. Lyophilization typically uses solutions with low solid content to optimize mass transfer and reduce drying time. …
    Image effect of glidant on tabletting behavior

    The effect of glidant on the tabletting behavior of common pharmaceutical excipients

    Newsfeeds - 09/08/2024 -
    The article on Pharma Excipients discusses the impact of glidants on the tabletting process in pharmaceutical manufacturing. Glidants are substances added to improve the flow properties of powders during tablet …
    assorted single-layer tablets on grey background

    Mimicking dry granulation on the STYL'One Evo to improve flowability

    Bulletins - 16/04/2024 - by Sixtine Caquant, Adrien Pelloux
    Dry granulation is a commonly used process in the pharmaceutical industry. It provides several key advantages, including precise particle size control, improved flowability of powders, versatility in processing materials, increased …
    Impact of dry coating lactose as a brittle excipient on multi-component blend processability

    Impact of dry coating lactose as a brittle excipient on multi-component blend processability

    Papers - 20/02/2024 - by Zhixing Lin, Bian Cabello, Rajesh N. Davé
    Prior research has shown the advantages of applying dry coating to finely graded microcrystalline cellulose (MCC) to facilitate direct compression (DC), a preferred method in tablet manufacturing. This process enhances …
    Rotary tablet press - KORSCH

    The critical role of product die filling

    White Papers - 01/02/2024 - by Friederike Guetter
    Product flow and consistent die filling are essential factors for successful tableting. For successful tablet production, many process steps must be harmonized with each other.
    no-image

    Use of Polyvinyl Alcohol as an effective binder in continuous Twin-Screw Granulation

    Papers - 01/02/2024 - by Gudrun Birk, Anja-Nadine Knüttel, Almut von der Brelie
    Granulation of powder blends is a frequently employed method in pharmaceutical formulations when there are issues with flowability, compactability, or uniformity in terms of the active pharmaceutical ingredient (API) content. …
    Impact of magnesium stearate physical and chemical variabilities on pharmaceutical powder flow and tablet physical properties

    Impact of magnesium stearate physical and chemical variabilities on pharmaceutical powder flow and tablet physical properties

    Papers - 08/12/2023 - by Natalia Veronica, Yi Ying Loh, Lydia Xiu Ying Loh, Paul Wan Sia Heng, Celine Valeria Liew
    Improving the Manufacturability of Cohesive and Poorly Compactable API for Direct Compression of Mini-tablets at High Drug Loading via Particle Engineering

    Improving the manufacturability of cohesive and poorly compactable API for direct compression of mini-tablets at high drug loading via particle engineering

    Papers - 01/11/2022 - by Liang Chen, Yiqing Lin, Erwin Irdam, Nicole Madden, Frederick Osei-Yeboah
    The aim is to employ a particle engineering approach to enhance the manufacturability of a cohesive and challenging-to-compact active pharmaceutical ingredient (API) with a high drug loading, specifically for the …
    Charge reduction assisted production of diminutive fluid bed granules for high drug load minitablets

    Charge reduction assisted production of diminutive fluid bed granules for high drug load minitablets

    Papers - 25/07/2022 - by Shang Jun Loo, Paul Wan Sia Heng, Lai Wah Chan
    Micronized drug powders are often impractical for use as tableting feed to create minitablets due to their cohesiveness and poor flow properties. The addition of fumed silica (fSi) within an …
    MEDELPHARM Science Lab powder angle of repose

    Assess the impact of your granulation process parameters with the STYL'One Evo

    Bulletins - 01/03/2022 - by Sixtine Caquant, Adrien Pelloux
    Powder granulation is commonly used in the pharmaceutical industry to improve flowability and compactibility of powders. In this case our customer wanted to develop a new directcompression grade of excipient …
    Enabling the direct compression of metformin hydrochloride through QESD crystallization

    Enabling the direct compression of metformin hydrochloride through QESD crystallization

    Papers - 01/06/2021 - by Jerome Hansen, Peter Kleinebudde
    Metformin hydrochloride, employed in treating type 2 diabetes, exhibits notable challenges with poor flowability and agglomeration during storage, making direct compression into tablets a hitherto unsuccessful endeavor. A previous study …