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    Weight uniformity in tablet manufacturing - the critical role in tablet efficacy

    Weight uniformity in tablet manufacturing - the critical role in tablet efficacy

    Newsfeeds - 22/10/2024 -
    The article discusses the critical importance of tablet weight uniformity in the tablet manufacturing process, emphasizing its role in ensuring that each tablet consistently delivers the intended dosage of key …
    white-tablets-close-up

    Drug product formulation & process development: the must-have skills at a glance

    Newsfeeds - 10/10/2024 -
    Drug product formulation and process development are critical yet often understated aspects of developing new drugs. Professionals in this field possess multidisciplinary skills, including organic chemistry, analytical development, solid-state characterization, …
    tablet white

    A recipe for success: mastering tableting requires understanding ingredient attributes

    Newsfeeds - 12/09/2024 -
    The author discusses the importance of understanding ingredient attributes in the process of tablet manufacturing. It emphasizes that consistently producing high-quality tablets requires more than just creating a successful small-scale …
    Orally-disintegrating-tablets-offer-range-of-patient-benefits

    Adapting to an ageing world: formulation strategies to boost patient compliance

    Newsfeeds - 11/09/2024 -
    The text discusses the challenges of medication compliance in older adults and how the pharmaceutical industry can address these through advanced drug formulations. With the global aging population rapidly increasing, …
    Image early solid form screening

    Early solid form screening guide drug substance through drug product development

    Newsfeeds - 15/07/2024 -
    The article discusses the importance of early solid form screening in drug development. This process involves identifying the most stable and effective solid form of a drug substance early in …
    Hybrid modeling of T-shaped partial least squares regression and transfer learning for formulation and manufacturing process development of new drug products

    Hybrid modeling of T-shaped partial least squares regression and transfer learning for formulation and manufacturing process development of new drug products

    Papers - 14/07/2024 - by Keita Yaginuma, Kensaku Matsunami, Laure Descamps, Alexander Ryckaert, Thomas De Beer
    T-shaped partial least squares regression (T-PLSR) is an effective machine learning technique for developing formulations and manufacturing processes for new drug products. Building an accurate T-PLSR model requires experimental data …
    Image - article Adare pharma solutions

    Formulation considerations for pediatric populations: finding the right dosage form for better adherence

    Newsfeeds - 12/07/2024 -
    The text discusses the challenges and strategies for developing pediatric drug formulations to improve adherence and outcomes. It highlights the need for specialized technology platforms and expert partners to address …
    Webinar_Measuring static & kinetic friction_Starting slide

    Measuring static and kinetic friction in routine compaction cycles and their implication for formulation development

    Webinar Replays - 05/07/2024 - by Danny van der Haven, Quentin Boulay
    The ejection of pharmaceutical tablets from the die is a critical moment after compaction during which defects can be induced if frictional forces are too high. Various studies have looked …
    standard tablets on blue background

    Ebook: Twin-screw extrusion for pharmaceutical applications

    Newsfeeds - 03/07/2024 -
    This compendium provides a comprehensive guide on how hot-melt extrusion (HME) can address common challenges in pharmaceutical development. It offers detailed guidance on all stages of the HME process, from …
    Multi-component mixing and demixing model for predictive finite element modelling of pharmaceutical powder compaction

    Multi-component mixing and demixing model for predictive finite element modelling of pharmaceutical powder compaction

    Papers - 01/07/2024 - by Dingeman L.H. Van Der Haven, Maria Mikoroni, Andrew Megarry, Ioannis S. Fragkopoulos, James A. Elliott
    This text describes a set of numerical methods for predictive finite element method (FEM) simulations of the compaction of multi-component pharmaceutical powder formulations across a full range of compositions. An …
    Webinar KIN 2 - Multilayer - Thumbnail slide

    Webinar series India - Multilayer tablets: from R&D formulation development to production scale-up

    Webinar Replays - 05/06/2024 - by Quentin Boulay, Bruno Leclercq, Pavan Porethi, Pravin Gawas
    Multilayer tablets are often the best solution to combine more than one API into a single dosage form. The main advantage is that the API contained in each layer of …
    Facilitating material-sparing dry granulation technical transfer through RoCo simulation of spray dried intermediate based formulations

    Facilitating material-sparing dry granulation technical transfer through RoCo simulation of spray dried intermediate based formulations

    Papers - 04/06/2024 - by Allisson N. DuRoss, Kendall R. Pearson, Mark E. Waller, Hannah E. Worrest
    Problem Statement • Dry granulation (DG) demonstration batches consume large amounts of material and time • Spray dried intermediate (SDI) based tablets commonly require upstream dry granulation • Previous workflows …