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    Effect of geometrical features on the capping behavior of biconvex tablets

    Effect of geometrical features on the capping behavior of biconvex tablets

    Papers - 03/09/2023 - by Vincent Mazel, Cléo Garcia, Pierre Tchoreloff
    Capping is a prevalent issue in the pharmaceutical tablet manufacturing process, influenced by both process and formulation parameters. This study systematically examined the impact of the geometrical features of biconvex …
    MEDELPHARM Science Lab powder angle of repose

    Assess the impact of your granulation process parameters with the STYL'One Evo

    Bulletins - 01/03/2022 - by Sixtine Caquant, Adrien Pelloux
    Powder granulation is commonly used in the pharmaceutical industry to improve flowability and compactibility of powders. In this case our customer wanted to develop a new directcompression grade of excipient …
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    Cushioning pellets based on microcrystalline cellulose – Crospovidone blends for MUPS tableting

    Papers - 26/06/2020 - by Ramy N. Elsergany, Lai Wah Chan, Paul Wan Sia Heng
    Compaction of multiple-unit pellet system (MUPS) tablets has been extensively reported to be potentially challenging. Thus, there is a need for non-segregating cushioning agents to mitigate the deleterious effect of …
    Cushioning pellets based on microcrystalline cellulose – Crospovidone blends for MUPS tableting

    Cushioning pellets based on microcrystalline cellulose – Crospovidone blends for MUPS tableting

    Papers - 26/06/2020 - by Ramy N. Elsergany, Lai Wah Chan, Paul Wan Sia Heng
    Compacting tablets within a multiple-unit pellet system (MUPS) has been widely acknowledged as potentially challenging. Consequently, there is a growing demand for non-segregating cushioning agents to alleviate the adverse effects …
    Early detection of capping risk in pharmaceutical compacts

    Early detection of capping risk in pharmaceutical compacts

    Papers - 01/12/2018 - by Xiaochi Xu, Chaitanya Krishna Prasad Vallabh, Stephen W. Hoag, Vivek S. Dave, Cetin Cetinkaya
    The detection of capping, a prevalent mechanical defect in tablet manufacturing, is crucial for pharmaceutical industry processes. This study introduces a non-destructive contact ultrasonic method for identifying capping risk in …
    Compaction of food powders: the influence of material properties and process parameters on product structure, strength, and dissolution

    Compaction of food powders: the influence of material properties and process parameters on product structure, strength, and dissolution

    Papers - 10/08/2017 - by W. Robert Mitchell, Laurent Forny, Tim Althaus, Daniel Dopfer, Gerhard Niederreiter, Stefan Palzer
    Throughout the pressure agglomeration of food powders, achieving control over final product properties remains challenging due to the intricate behaviors of the materials involved. This study aims to enhance the …
    Evaluation of a rotary tablet press simulator as a tool for the characterization of compaction properties of pharmaceutical products

    Evaluation of a rotary tablet press simulator as a tool for the characterization of compaction properties of pharmaceutical products

    Papers - 01/06/2010 - by F. Michaut, V. Busignies, C. Fouquereau, B. Huet de Barochez, B. Leclerc, P. Tchoreloff
    The Stylcam 100R, designed as a rotary press simulator to replicate speed profiles of rotary tablet presses, has undergone qualification by various laboratories. However, its suitability for investigating powder behavior …