Fate of tableted freeze-dried siRNA lipoplexes in gastrointestinal environment
first_published_at:Oct. 28, 2021, midnight / date_published:Oct. 28, 2021
Papers
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28/10/2021 -
by
Asad Ur Rehman,
Virginie Busignies,
Marcela Coelho Silva Ribeiro,
Nayara Almeida Lage,
Pierre Tchoreloff,
Virginie Escriou,
Christine Charrueau
It is essential to incorporate siRNA into nanocarriers to facilitate its intracellular delivery, as siRNA alone cannot penetrate cells. However, the incorporation of these nanocarriers into oral solid dosage forms …
