Supersaturated controlled release matrix using amorphous dispersions of glipizide
first_published_at:Sept. 1, 2016, midnight / date_published:Sept. 1, 2016
Papers
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01/09/2016 -
by
Zheng Lu,
Yonglai Yang,
Rae-Ann Covington,
Yunxia (Vivian) Bi,
Thomas Dürig,
Marc A. Ilies,
Reza Fassihi
Spray-dried dispersions (SDDs) of glipizide, a model drug classified as BCS Class II, were created utilizing various hydroxypropyl methylcellulose acetate succinate (HPMCAS) grades and copovidone S-630 as carriers. Analysis through …