Formulating amorphous solid dispersions: Impact of inorganic salts on drug release from tablets containing Itraconazole-HPMC extrudate
first_published_at:Dec. 3, 2019, midnight / date_published:Dec. 3, 2019
Papers
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03/12/2019 -
by
Ryusuke Takano,
Reto Maurer,
Laurence Jacob,
Frank Stowasser,
Cordula Stillhart,
Susanne Page
Amorphous solid dispersions (ASD) are increasingly utilized to enhance the oral bioavailability of poorly water-soluble compounds. However, the hydrophilic polymers present in ASD often exhibit high water binding properties, leading …
