Wetting effects versus ion pairs diffusivity: Interactions of anionic surfactants with highly soluble cationic drugs and its impact on tablet dissolution
first_published_at:July 1, 2015, midnight / date_published:July 1, 2015
Papers
-
01/07/2015 -
by
Divyakant Desai,
Benjamin Wong,
Yande Huang,
Qingmei Ye,
Hang Guo,
Ming Huang,
Peter Timmins
A study was undertaken to gain a mechanistic understanding of the dissolution of metformin hydrochloride, a highly soluble cationic drug, in the presence of anionic surfactants known as sodium alkyl …
