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Scientific papers

Scientific papers

Explore a selection of scientific papers featuring research conducted with STYL’One Compaction Simulators. Discover how leading scientists and institutions use STYL’One technology to advance understanding in powder compression, tablet formulation development, and process innovation.

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    Understanding the multidimensional effects of polymorphism, particle size and processing for D-Mannitol powders

    Papers - 07/10/2022 - by Lena Mareczek, Carolin Riehl, Meike Harms, Stephan Reichl
    This study investigated the influence of polymorphic form, particle size, and processing of mannitol on the mechanical properties of solid oral dosage forms. The particle and powder properties of spray …
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    Transformation Induite au cours d'un Procédé Industriel (TIPI) de compression directe: transition polymorphique de la caféine et propriétés physiques des comprimés

    Papers - 05/12/2016 - by Audrey Juban
    L'objectif principal de cette étude est de fournir des éléments de compréhension sur la transition polymorphique de la caféine (principe actif modèle) de la Forme I à la Forme II …
    Impact of micromeritic properties of an active pharmaceutical ingredient on its compaction behavior

    Impact of micromeritic properties of an active pharmaceutical ingredient on its compaction behavior

    Papers - 17/02/2015 - by Dilbir S. Bindra, Sridhar Desikan
    The processability of a high drug loading formulation can be notably influenced by the physical characteristics of an active pharmaceutical ingredient (API). This paper illustrates a case where distinct micromeritic …
    Exploring the possible relationship between the drug release of Compritol®-containing tablets and its polymorph forms using micro X-ray diffraction

    Exploring the possible relationship between the drug release of Compritol®-containing tablets and its polymorph forms using micro X-ray diffraction

    Papers - 10/01/2015 - by Vincent Jannin, Yvonne Rosiaux, Jean Doucet
    Lipid excipients are increasingly utilized in the pharmaceutical industry for sustained drug delivery, yet their development faces challenges due to the well-established polymorphism of lipids, often perceived as a drawback …