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    Quality by design applied to pediatric-friendly formulations - image

    Quality by design applied to pediatric-friendly formulations

    Newsfeeds - 28/08/2025 -
    The article explores how Quality by Design (QbD) frameworks can be systematically applied to the development of solid pediatric formulations, with a focus on enhancing safety, efficacy, palatability, and process …
    5 key elements qbd in pharma image

    5 key elements of quality by design in pharma

    Newsfeeds - 10/03/2025 -
    The article "5 Key Elements Of Quality By Design In Pharma" discusses the importance of incorporating quality into every stage of the pharmaceutical manufacturing process, starting from research and development. …
    Yellow and white tablets on pink background

    Challenges and solutions in drug product process development from a material science perspective

    Papers - 07/04/2022 - by Antonios Fytopoulos, Rohit Ramachandran, Panos M. Pardalos, Fanny Stauffer, Pierre-François Chavez, Julie Fahier, Corentin Larcy, Mehrdad Pasha, Gabrielle Pilcer
    While it is widely acknowledged that comprehending the impact of material attributes on drug product processes is crucial for designing resilient products and processes, the systematic identification of critical process …
    Critical tools in tableting research: using compaction simulator and Quality by Design (QbD) to evaluate lubricants’ effect in direct compressible formulation

    Critical tools in tableting research: using compaction simulator and Quality by Design (QbD) to evaluate lubricants’ effect in direct compressible formulation

    Papers - 11/05/2021 - by Nailla Jiwa, Yildiz Ozalp, Gizem Yegen, Buket Aksu
    As widely acknowledged, the product development phase is intricate, demanding a depth of knowledge and substantial time investment. The meticulous selection of excipients, considering their appropriate functionalities and corresponding levels, …
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    Integrating QbD tools for flexible scale-up batch size selection for solid dosage forms

    Papers - 01/03/2020 - by Naseem A. Charoo, Ziyaur Rahman
    The current definition of the pilot scale batch size for solid oral dosage forms, set by major regulatory agencies as one-tenth of full production or 100,000 units, whichever is larger, …
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    QbD approach formulation design for metformin HCI and evaluations

    Papers - 01/01/2019 - by Omar Hourani
    This study aimed to formulate Metformin HCI 500 mg tablets using the Direct Compression (DC) method, selecting appropriate excipients, and evaluating the formulation outcomes. In order to achieve an optimized …
    Active content determination of pharmaceutical tablets using near infrared spectroscopy as Process Analytical Technology tool

    Active content determination of pharmaceutical tablets using near infrared spectroscopy as Process Analytical Technology tool

    Papers - 05/11/2015 - by Pierre-François Chavez, Pierre-Yves Sacré, Charlotte De Bleye, Lauranne Netchacovitch, Jérôme Mantanus, Henri Motte, Martin Schubert, Philippe Hubert, Eric Ziemons
    This study aimed to establish Near-Infrared (NIR) methods for determining the active content in non-coated pharmaceutical tablets produced from a proportional tablet formulation. These NIR methods were developed to monitor …