Assessment of volumetric scale-up law for processing of a sustained release formulation on co-rotating hot-melt extruders
first_published_at:Oct. 1, 2019, midnight / date_published:Oct. 1, 2019
Papers
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01/10/2019 -
by
Jeroen Van Renterghem,
Shana Van de Steene,
Tryfon Digkas,
Margarethe Richter,
Chris Vervaet,
Thomas De Beer
In this study, we evaluated the applicability of the volumetric scale-up law for transitioning from a laboratory-scale extruder (11 mm diameter) to a pilot-scale extruder (16 mm diameter) with geometric …
