Enabling the direct compression of metformin hydrochloride through QESD crystallization
first_published_at:June 1, 2021, midnight / date_published:June 1, 2021
Papers
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01/06/2021 -
by
Jerome Hansen,
Peter Kleinebudde
Metformin hydrochloride, employed in treating type 2 diabetes, exhibits notable challenges with poor flowability and agglomeration during storage, making direct compression into tablets a hitherto unsuccessful endeavor. A previous study …
