Current trends and challenges influencing the oral solid dose market

January 23, 2024

Remove from favorites

Add to favorites

The article discusses current trends and challenges in the oral solid dose (OSD) market, focusing on the influence of patient-centric formulations and advancements in excipients. Key points include the importance of improving patient experience through factors like texture, taste, and swallowability, especially for vulnerable populations like children and the elderly. The emergence of oral administration for biologics presents challenges such as environmental sensitivity and absorption issues, requiring novel formulations and excipients. With the impending "patent cliff," pharmaceutical companies are urged to explore alternative administration routes like OSD to maintain competitiveness. The article also highlights recent excipient advancements, emphasizing their role in enhancing mouthfeel, extending stability, enabling OSD biologics, facilitating controlled release, increasing bioavailability, and providing healthier options. Incorporating new excipients into formulations requires careful consideration of compatibility with the active pharmaceutical ingredient (API), processability, packaging, thorough assessment, and cost-effectiveness. Overall, the focus is on leveraging excipients to address challenges and meet evolving consumer needs in the OSD market.