Close search
Resources

Newsfeeds

Favorite Articles

    Tags

    Categories

    Authors

    22 results
    Date
    Mimicking dry granulation on the STYL'One Evo to improve flowability

    Mimicking dry granulation on the STYL'One Evo to improve flowability

    Bulletins - 16/04/2024 - by Sixtine Caquant, Adrien Pelloux
    Dry granulation is a commonly used process in the pharmaceutical industry. It provides several key advantages, including precise particle size control, improved flowability of powders, versatility in processing materials, increased …
    no-image

    Modeling of STYL'One Evolution correction factors for multicomponent mixtures scaling-up to roller compaction

    Papers - 11/04/2024 - by Fabia Arpago, Agostino Dall'Ara
    Roll compaction (RC) stands as a cost-efficient dry granulation technique extensively utilized in the pharmaceutical sector. In the initial stages of formulation development, particularly when resources are constrained, the ability …
    image twin screw granulation process

    A QbD Guided Development of a Twin-Screw Granulation Process

    Newsfeeds - 12/03/2024 -
    The text discusses dry granulation techniques in the pharmaceutical industry, focusing on roller compaction and slugging, highlighting their limitations such as inferior tablet strength and reduced yield due to fine …
    Material-Sparing-Method-for-Dry-Granulation.original

    Dry Granulation a material sparing method

    White Papers - 01/08/2023 - by Bruno Villa
    Granulation of pharmaceutical powder is often required to prevent segregation of the Active Pharmaceutical Ingredient (API) and/or to enhance the blend flowability, which is critical to ensure consistent tablet mass …
    no-image

    Effect of Process Parameters, Protectants and Carrier Materials on the Survival of Yeast Cells during Fluidized Bed Granulation for Tableting

    Papers - 09/03/2023 - by Karl Vorländer, Lukas Bahlmann, Arno Kwade, Jan Henrik Finke, Ingo Kampen
    This study focuses on the drying of Saccharomyces cerevisiae, a yeast variety that includes the probiotic Saccharomyces boulardii. Ensuring microbial viability is crucial for effective dosage forms, especially for probiotics …
    no-image

    A novel approach to minimize loss of compactibility in a dry granulation process using superdisintegrants

    Papers - 07/08/2022 - by Maarten Jaspers, Timo P. Roelofs, Pauline H.M. Janssen, Robin Meier, Bastiaan H.J. Dickhoff
    Roller compaction for dry granulation is gaining popularity as a method for producing oral solid dosage forms. The process offers simplicity compared to wet granulation and operates inherently in a …
    no-image

    Pharmaceutical Development of Film-Coated Mini-Tablets with Losartan Potassium for Epidermolysis Bullosa

    Papers - 05/03/2022 - by Valentinë Elezaj, Ard Lura, Luis Canha, Jörg Breitkreutz
    Epidermolysis bullosa is a genetically heterogeneous skin fragility disorder that manifests with multiorgan involvement, often evident in newborn children. The condition leads to severe progressive fibrosis following skin blistering, mucosal …
    no-image

    Using a Model-based Material Sparing Approach for Formulation and Process Development of a Roller Compacted Drug Product

    Papers - 26/02/2022 - by Kalyan V. Vasudevan, Yu Elaine Pu, Hossein Amini, Catherine Guarino, Anjali Agrawal, Ilgaz Akseli
    This study outlines an efficient approach that integrates material profiling, Instron uniaxial die-punch testing, and a mathematical model for roller compaction to guide the formulation and process development of a …
    20211027_Webinar_Dry_Granulation_Mimicking_FINAL Slides Medelpharm + Hannah Lou

    Dry Granulation Formulation Development

    Webinar Replays - 27/10/2021 - by Hannah Lou Keiser, Bruno Leclercq
    Hannah Lou Keizer (Doctorate at Heinrich Heine University Düsseldorf ), Bruno Leclercq and Adrien Pelloux (MEDELPHARM) share on Dry Granulation Formulation Development and Roll Compaction mimicking.
    BRC_100_033 - L.B. Bohle

    Roller compaction: new trends, challenges and solutions

    Newsfeeds - 12/11/2020 -
    This article explains the 3 known technologies to develop tablets:- direct compression- wet granulation- dry granulation, with a focus on roller compaction, as it remains an effective solution for most …
    no-image

    Recent Progress in Roll Compaction Process Development for Pharmaceutical Solid Dosage Form Manufacture

    Papers - 11/06/2020 - by Ariel R. Muliadi, Alamelu Banda, Chen Mao
    Over the past decade, roll compaction technologies have seen significant advancements, becoming increasingly favored by formulation scientists for granulation purposes. This chapter provides an overview of recent developments in pharmaceutical …
    no-image

    Functionality of disintegrants with different mechanisms after roll compaction

    Papers - 01/06/2020 - by Sabrina Berkenkemper, Hannah Lou Keizer, Marc Lindenberg, Anikó Szepes, Peter Kleinebudde
    The objective of this study was to assess the functionality of two disintegrants, namely crospovidone and croscarmellose sodium, in tablet formulations processed through roll compaction followed by tableting. The investigation …