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    Advancing solid fraction analysis: Testing laser triangulation as an at-line technique

    Advancing solid fraction analysis: Testing laser triangulation as an at-line technique

    Papers - 01/06/2026 - by Camille Adler, Bindhu Gururajan, Vincent Rogue, Jan Lenz, Lizbeth Martinez
    Roller compaction is a dry granulation technique used to improve the flow properties of pharmaceutical materials when direct tablet compression is not feasible. It is often preferred to wet granulation …
    Merck formulation handbook - image

    Formulation handbook from Merck

    Newsfeed - 02/10/2025 -
    Formulating the perfect dosage form is no easy task. With so many techniques and excipients available, every decision made during development can influence the performance and success of the final …
    Dry granulation in solid oral formulation- advantages of spray-dried mannitol - image

    Dry granulation in solid oral formulation: advantages of spray-dried mannitol in roll compaction

    Newsfeed - 25/09/2025 -
    The article explores the benefits of spray-dried mannitol as a filler/binder in dry granulation via roller compaction, a technique particularly suited to moisture- and heat-sensitive APIs since it avoids wet …
    Photo AAPS 2024 - James on KORSCH booth

    MEDELPHARM's participation at AAPS PharmSci 360 2024: Innovations in tablet formulation

    Newsfeed - 30/10/2024 - by Gabrielle Dupont
    At the recent AAPS PharmSci 360, held from October 20th-23rd, 2024, in Salt Lake City, MEDELPHARM showcased its latest advancements in tablet formulation technology alongside KORSCH America. This collaboration featured …
    Comprehensive Review of Modern Techniques of Granulation in Pharmaceutical Solid Dosage Forms

    Comprehensive review of modern techniques of granulation in pharmaceutical solid dosage forms

    Newsfeed - 29/08/2024 -
    The review provides an extensive overview of granulation techniques in pharmaceutical manufacturing, comparing traditional and modern methods. It details dry granulation techniques such as slugging, roller compaction, and pneumatic dry …
    Facilitating material-sparing dry granulation technical transfer through RoCo simulation of spray dried intermediate based formulations

    Facilitating material-sparing dry granulation technical transfer through RoCo simulation of spray dried intermediate based formulations

    Posters - 04/06/2024 - by Allisson N. DuRoss, Kendall R. Pearson, Mark E. Waller, Hannah E. Worrest
    Problem Statement • Dry granulation (DG) demonstration batches consume large amounts of material and time • Spray dried intermediate (SDI) based tablets commonly require upstream dry granulation • Previous workflows …
    Comprehensive Review of Modern Techniques of Granulation in Pharmaceutical Solid Dosage Forms

    Comprehensive review of modern techniques of granulation in pharmaceutical solid dosage forms

    Papers - 04/06/2024 - by Anil Kumar Vadaga, Sai Shashank Gudla, Gnanendra Sai Kumar Nareboina, Hymavathi Gubbala, Bhuvaneswari Golla
    This comprehensive review examines both modern and traditional granulation techniques in pharmaceutical dosage forms, with a particular focus on dry and wet granulation. The dry granulation methods covered include slugging, …
    Facilitating material-sparing dry granulation technical transfer through RoCo simulation of spray dried intermediate based formulations

    Facilitating material-sparing dry granulation technical transfer through RoCo simulation of spray dried intermediate based formulations

    Papers - 04/06/2024 - by Allisson N. DuRoss, Kendall R. Pearson, Mark E. Waller, Hannah E. Worrest
    Problem Statement • Dry granulation (DG) demonstration batches consume large amounts of material and time • Spray dried intermediate (SDI) based tablets commonly require upstream dry granulation • Previous workflows …
    tablets and powder heap

    Modified roller compaction model to account for roll speed effect on powder compaction in dry granulation process

    Papers - 07/05/2024 - by Indu Muthancheri, Mario Rousselin, Anna Espinose, Nicolas Sanchez, Jean-Rene Authelin
    This study presents an enhancement to the roller compaction model originally proposed by [1], incorporating the impact of roll speed on powder compaction during the dry granulation process. The updated …
    assorted single-layer tablets on grey background

    Mimicking dry granulation on the STYL'One Evo to improve flowability

    Bulletins - 16/04/2024 - by Sixtine Caquant, Adrien Pelloux
    Dry granulation is a commonly used process in the pharmaceutical industry. It provides several key advantages, including precise particle size control, improved flowability of powders, versatility in processing materials, increased …
    no-image

    Modeling of STYL'One Evolution correction factors for multicomponent mixtures scaling-up to roller compaction

    Papers - 11/04/2024 - by Fabia Arpago, Agostino Dall'Ara
    Roll compaction (RC) stands as a cost-efficient dry granulation technique extensively utilized in the pharmaceutical sector. In the initial stages of formulation development, particularly when resources are constrained, the ability …
    image twin screw granulation process

    A QbD guided development of a Twin-Screw Granulation process

    Newsfeed - 12/03/2024 -
    The text discusses dry granulation techniques in the pharmaceutical industry, focusing on roller compaction and slugging, highlighting their limitations such as inferior tablet strength and reduced yield due to fine …