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    MUPS KORSCH technology blog

    MUPS - the mixture is what matters

    White Papers - 06/02/2024 - by Friederike Guetter
    MUPS, or “multiple unit pellet system”, is a solid dosage form in which the granulation consists of a mixure of active, coated pellets and powder excipients. MUPS products include, for …
    Solidification of radioactive soil waste through volume reduction and stabilization: Characteristic evaluation and waste acceptance criteria satisfaction

    Solidification of radioactive soil waste through volume reduction and stabilization: Characteristic evaluation and waste acceptance criteria satisfaction

    Papers - 01/05/2023 - by Sang-Hyun Lim, Sang-Heon Lee, Jong-Soon Song, Ki-Hong Kim
    The disposal of radioactive soil waste poses a global environmental challenge, necessitating effective management strategies. To address this issue, pelletization technology can be employed to reduce the physical volume of …
    Insight into tableted pellets by combining X-ray micro-computed tomography and experimental compaction

    Insight into tableted pellets by combining X-ray micro-computed tomography and experimental compaction

    Papers - 20/12/2021 - by Imen Boudina, Eric Rondet, Saeid Nezamabadi, Tahmer Sharkawi
    Pellets, spherical agglomerated particles utilized in the production of multiparticulate pharmaceutical dosage forms, were the subject of this study aiming to introduce a novel approach for evaluating pellet deformation under …
    Cushioning pellets based on microcrystalline cellulose – Crospovidone blends for MUPS tableting

    Cushioning pellets based on microcrystalline cellulose – Crospovidone blends for MUPS tableting

    Papers - 26/06/2020 - by Ramy N. Elsergany, Lai Wah Chan, Paul Wan Sia Heng
    Compacting tablets within a multiple-unit pellet system (MUPS) has been widely acknowledged as potentially challenging. Consequently, there is a growing demand for non-segregating cushioning agents to alleviate the adverse effects …
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    Cushioning pellets based on microcrystalline cellulose – Crospovidone blends for MUPS tableting

    Papers - 26/06/2020 - by Ramy N. Elsergany, Lai Wah Chan, Paul Wan Sia Heng
    Compaction of multiple-unit pellet system (MUPS) tablets has been extensively reported to be potentially challenging. Thus, there is a need for non-segregating cushioning agents to mitigate the deleterious effect of …
    A mechanistic understanding of compression damage to the dissolubility of coated pellets in tablets

    A mechanistic understanding of compression damage to the dissolubility of coated pellets in tablets

    Papers - 01/01/2020 - by Tze Ning Hiew, Yu Harn Tian, Huei Ming Tan, Paul Wan Sia Heng
    The potential harm to the drug diffusion coat barrier of controlled-release pellets due to compaction force during the preparation of multiple-unit pellet system tablets is a significant concern. Prior research …