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Commercial scale transfer of a twin-screw melt granulation process for high drug load fevipiprant tablets

July 21, 2022, midnight - by Claudia Vicente Martin , Stephan Stocker , Manel Bautista , Vincent Rogue , Caroline Steib-Lauer , Hans-Georg Häcker , Dirk Spickermann , Stefan Hirsch , Sundeep S Dhareshwar
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This study provides an overview of specific twin-screw melt granulation techniques and process analytical technology employed in the successful scaling-up and commercial transfer of immediate-release fevipiprant tablets with a high drug load (80.5% w/w).
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commercial technology transfer stylone high drug load tablets near-infrared spectroscopy process analytical technology scaling up twin-screw melt granulation scale-up styl'one evo
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