Close search
Scientific papers

Scientific papers

Favorite Articles

    Tags

    Categories

    Authors

    4 results
    Date
    Air entrapment during tablet compression – Diagnosis, impact on tableting performance, and mitigation strategies

    Air entrapment during tablet compression – Diagnosis, impact on tableting performance, and mitigation strategies

    Papers - 05/03/2022 - by Gerrit Vreeman, Changquan Calvin Sun
    The occurrence of air entrapment during powder compression, a phenomenon capable of causing tablet defects during decompression and ejection, was investigated using celecoxib powder. This involved a comparison of in-die …
    Lamination of pharmaceutical tablets: classification and influence of process parameters

    Lamination of pharmaceutical tablets: classification and influence of process parameters

    Papers - 23/10/2021 - by V. Mazel, P. Tchoreloff
    The occurrence of lamination is a prevalent issue in the pharmaceutical tablet manufacturing process, representing a failure of the tablet along one or more planes parallel to the surface and …
    Enabling the direct compression of metformin hydrochloride through QESD crystallization

    Enabling the direct compression of metformin hydrochloride through QESD crystallization

    Papers - 01/06/2021 - by Jerome Hansen, Peter Kleinebudde
    Metformin hydrochloride, employed in treating type 2 diabetes, exhibits notable challenges with poor flowability and agglomeration during storage, making direct compression into tablets a hitherto unsuccessful endeavor. A previous study …
    no-image

    Role of precompression in the mitigation of capping: a case study

    Papers - 01/10/2020 - by Vincent Mazel, Pierre Tchoreloff
    Capping, a significant issue in pharmaceutical tablet manufacturing, involves the detachment of one of the tablet's convex portions during ejection from the press or after relaxation. Currently, solutions to this …