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    Image - Article I Holland GR lanes

    Working with GR Lanes Health Products Ltd.

    White Papers - 23/04/2024 -
    Lanes, is a leading UK family-owned pharmaceutical company that specialises in producing natural remedies and is famous for brands such as Olbas and Kalms. Market leading products like these demand …
    Take-off sensor as a tool for sticking assessment during tablet development

    Take-off sensor as a tool for sticking assessment during tablet development

    Papers - 21/03/2024 - by Adrien Pelloux, Delphine Ach-Hubert, Sixtine Caquant
    More than 70% of candidate drugs have low solubility (BCS Class II and IV) (Nikolakakis et al. 2017). Making tablets with low solid fraction improves the dissolution rate (Van der …
    Galenic laboratory Armor - video screen

    See the Galenic Laboratory at Armor Pharma

    Newsfeeds - 15/03/2024 -
    Since 2020, Armor Pharma has made significant investments in a cutting-edge galenic laboratory, enhancing their expertise as a leading pharmaceutical lactose provider.Check out the latest video showcasing Armor Pharma's State-of-the-art …
    The impact of diluents on the compaction, dissolution, and physical stability of amorphous solid dispersion tablets

    The impact of diluents on the compaction, dissolution, and physical stability of amorphous solid dispersion tablets

    Papers - 22/02/2024 - by Dongyue Yu, Stephen W. Hoag
    The amorphous solid dispersion (ASD) method proves effective in enhancing the solubility, dissolution, and bioavailability of poorly water-soluble medications. However, these forms are prone to transitioning into more thermodynamically stable, …
    Comprehensive evaluation of polymer types and ratios in Spray-Dried Dispersions: Compaction, Dissolution, and physical stability

    Comprehensive evaluation of polymer types and ratios in Spray-Dried Dispersions: Compaction, Dissolution, and physical stability

    Papers - 25/01/2024 - by Dongyue Yu, Haichen Nie, Stephen W. Hoag
    The amorphous solid dispersion (ASD) method is a well-established approach to enhance the solubility and bioavailability of poorly soluble drugs. Although a significant number of ASD products are in tablet …
    Effect of particle size on the dispersion behavior of magnesium stearate blended with microcrystalline cellulose

    Effect of particle size on the dispersion behavior of magnesium stearate blended with microcrystalline cellulose

    Papers - 07/01/2024 - by Daniel Puckhaber, Jan Henrik Finke, Sarah David, Bindhumadhavan Gururajan, Supriya Rane, Arno Kwade
    Most tablets produced include lubricants to minimize friction during ejection. However, in the case of plastically deforming materials such as microcrystalline cellulose (MCC), internal incorporation of lubricants is known to …
    Impact of magnesium stearate physical and chemical variabilities on pharmaceutical powder flow and tablet physical properties

    Impact of magnesium stearate physical and chemical variabilities on pharmaceutical powder flow and tablet physical properties

    Papers - 08/12/2023 - by Natalia Veronica, Yi Ying Loh, Lydia Xiu Ying Loh, Paul Wan Sia Heng, Celine Valeria Liew
    Thumbnail webinar replay Self-Driving Tableting DataFactory

    Self-driving tableting DataFactory

    Webinar Replays - 07/12/2023 - by Daniel Markl, Bruno Leclercq
    "Self-driving tableting DataFactory"- with guest speaker Daniel Markl, reader at the University of Strathclyde and Associate Director at the CMAC Center for Continuous Manufacturing and Advanced CrystallisationTraditional methods of developing …
    Extended Dwell Flat (XDF) tooling at IHolland

    Timing is key in tabletting

    White Papers - 29/11/2023 -
    Why you need to get your timing right to make better tabletsNeed to mass-produce tablets with quality solid dosage in a quick and cost-effective way? The time that a formulation …
    Tableting properties of freeze-dried trehalose: physico-chemical and mechanical investigation

    Tableting properties of freeze-dried trehalose: physico-chemical and mechanical investigation

    Papers - 11/11/2023 - by Hassana Hsein, Charbel Madi, Vincent Mazel, Pierre Tchoreloff, Virginie Busignies
    The preferred method for enhancing the stability and storage conditions of biopharmaceutical products is freeze-drying. Typically, these freeze-dried products are designed for administration via the parenteral route. However, many parenterally …
    no-image

    Effects of Tableting Process Parameters and Powder Lubrication Levels on Tablet Surface Temperature and Moisture Content

    Papers - 08/11/2023 - by Komlan Koumbogle, Ryan Gosselin, François Gitzhofer, Nicolas Abatzoglou
    The occurrence of punch sticking poses a recurrent challenge in the pharmaceutical tablet manufacturing process. The moisture content of the powder plays a crucial role in the development of sticking; …
    Application of Response Surface Methodology to Improve the Tableting Properties of Poorly Compactable and High-Drug-Loading Canagliflozin Using Nano-Sized Colloidal Silica

    Application of Response Surface Methodology to Improve the Tableting Properties of Poorly Compactable and High-Drug-Loading Canagliflozin Using Nano-Sized Colloidal Silica

    Papers - 29/10/2023 - by Majed Alrobaian, Ahmed Alalaiwe, Ziyad S. Almalki, Mohamed H. Fayed
    Creating a robust direct compression (DC) formulation for an active pharmaceutical ingredient (API) with challenging flow and compaction properties at a high API load poses a considerable challenge. This study …