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Tableting of coated multiparticulates: Influences of punch face configurations

Tableting of coated multiparticulates: Influences of punch face configurations

Papers - 01/03/2024 - by Daniel Robin Thio, Natalia Veronica, Paul Wan Sia Heng, Lai Wah Chan

The impact of punch face design on multi-unit pellet system (MUPS) tablets was examined in this study. Drug-loaded pellets, coated with sustained-release polymers such as ethylcellulose or acrylic, were compacted …

MUPS KORSCH technology blog

MUPS - the mixture is what matters

White Papers - 06/02/2024 - by Friederike Guetter

MUPS, or “multiple unit pellet system”, is a solid dosage form in which the granulation consists of a mixure of active, coated pellets and powder excipients. MUPS products include, for …

An evaluation of microcrystalline cellulose attributes affecting compaction-induced pellet coat damage through a multi-faceted analysis

An evaluation of microcrystalline cellulose attributes affecting compaction-induced pellet coat damage through a multi-faceted analysis

Papers - 17/07/2023 - by Daniel Robin Thio, Quinton Aguilera, Janice Ke Xin Yeoh, Paul Wan Sia Heng, Lai Wah Chan

The issue of pellet coat damage in multi-unit pellet system (MUPS) tablets has been previously examined, with only limited success in addressing the problem. While the impact of lactose filler …