NIR-Hyperspectral Imaging and Raman Chemical Mapping of MultilayerTablets
March 30, 2016, midnight
Johannes G. Khinast
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Advanced pharmaceutical dosage forms require improved process analytical technology tools to monitor critical quality attributes. The effectiveness of Near-Infrared (NIR) Hyperspectral Imaging (HSI) was assessed in conjunction with a Principal Component Analysis (PCA) chemometric model for multilayer tablets. Raman mapping served as the baseline reference method.