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Rheological properties of pharmaceutical excipients

May 23, 2025
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The article from Pharmaceutical Online discusses how the rheological properties of pharmaceutical excipients—specifically lactose monohydrate and carboxymethyl cellulose (CMC)—affect powder flow, compressibility, and shear behavior, all critical for tablet manufacturing. Using a Discovery™ HR-30 Rheometer, researchers found lactose monohydrate had much higher compressibility than CMC, likely due to differences in particle shape and size distribution. Tests under varying temperatures highlighted how environmental conditions impact material behavior.

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