When patient insight meets smart drug formulation

March 05, 2026

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The article highlights how patient-centric design is reshaping drug formulation, especially for oral solid dosage forms. It points out that medication non-adherence — often driven by unpleasant taste, swallowing difficulties, frequent dosing, or inconvenient formats — remains a major barrier to effective therapy. To address this, manufacturers are increasingly using advanced excipients and innovative technologies to create dosage forms that better match patient needs. Examples include 3D-printed chewable tablets with taste-masking excipients to improve palatability and customizable dosing for pediatric patients, complexes such as cyclodextrins to reduce bitterness and associated side effects (like nausea), and modified-release tablets that reduce dosing frequency to ease chronic treatment regimens. The article underscores that thoughtful formulation — from ingredient selection to controlled-release design — can significantly boost compliance and therapeutic outcomes, making patient experience a core driver of solid dosage design rather than an afterthought.