Adapting to an ageing world: formulation strategies to boost patient compliance

September 11, 2024

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The text discusses the challenges of medication compliance in older adults and how the pharmaceutical industry can address these through advanced drug formulations. With the global aging population rapidly increasing, the demand for medications targeting chronic diseases is rising, putting pressure on healthcare systems. Key factors undermining compliance in seniors include complex treatment regimens, cognitive decline, and difficulty swallowing pills.

To improve compliance, the text highlights the potential of controlled-release (CR) formulations, orally disintegrating tablets (ODTs), and taste-masking techniques. CR formulations offer steady drug release, reducing the need for frequent dosing, while ODTs help patients with swallowing difficulties. Taste-masking enhances the palatability of medications, making them more acceptable to seniors.

Excipients play a crucial role in these innovations by modulating drug release, facilitating disintegration, and masking unpleasant tastes. By adopting these strategies, pharmaceutical companies can create more patient-friendly medications, ultimately improving health outcomes and reducing healthcare costs.