The effect of glidant on the tabletting behavior of common pharmaceutical excipients

August 09, 2024

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The article on Pharma Excipients discusses the impact of glidants on the tabletting process in pharmaceutical manufacturing. Glidants are substances added to improve the flow properties of powders during tablet production. The article examines how different types of glidants affect the tabletting process, focusing on their influence on the mechanical properties of tablets, such as hardness and disintegration time.

Key points include:

- The role of glidants in reducing interparticle friction, which enhances powder flowability.

- The study of various glidants, such as colloidal silicon dioxide, talc, and magnesium stearate, and their specific effects on tablet formulation.

- Insights into how the concentration and type of glidant used can alter the final product's quality, impacting factors like tablet weight uniformity and dissolution rate.

Overall, the article emphasizes the importance of selecting appropriate glidants and optimizing their concentration to ensure efficient tabletting and high-quality pharmaceutical products.