Scientific papers
Standardized doses in tablets are suitable for
most APIs and patient groups. However, there
are many instances in which personalized medication
enables huge benefits for the patients. Especially
if the API has a narrow therapeutic range or
very vulnerable patient groups like children or elderly
patients are supplied, it is necessary to personalize
the API dose to reach optimal therapeutic
blood concentrations and prevent side effects.
This study aims to demonstrate that personalized
tablets can be precisely formulated in a volumetric
dosed bilayer tablet approach.
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