Unravelling capping issues using STYL’One Dwell Time or Punch Speed
Jan. 1, 2016, midnight
Susana Nieto Bobadilla
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Capping is a prevalent issue encountered in tablet formulation and industrial production, with various factors attributed to its origin, such as air entrapment, compression speed, viscoelastic recovery, and stress and density distribution. The speed at which the punch travels during compression has a significant impact on tablet properties.
However, this speed is not constant; it accelerates to a maximum when in contact with the roller and then reduces to zero when the roller reaches the flat portion of the punch head during dwell time. The impact of compression speed and dwell time varies for each formulation. The objective of this study was to investigate the influence of punch speed and dwell time on the occurrence of capping.