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    MEDELPHARM bringing expertise in research and development at Compaction Simulation Forum in Dublin

    Newsfeeds - 22/04/2024 -
    MEDELPHARM, a leading name in pharmaceutical equipment and technology, is getting ready to participate at the upcoming Compaction Simulation Forum (CSF), scheduled to take place from June 4th to 6th …
    MEDELPHARM PBP World Meeting LinkedIn

    MEDELPHARM highlights innovative solutions at PBP World Meeting

    Newsfeeds - 06/03/2024 -
    MEDELPHARM, a leading provider of innovative solutions for pharmaceutical research and development, will be participating in the upcoming PBP World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology in Vienna from …
    Current State of Minitablet Product Design: A Review

    Current state of minitablet product design: a review

    Papers - 16/02/2024 - by Saikishore Meruva, Aditya B. Singaraju, Bhavani Prasad Vinjamuri, Robert Ternik, William C. Stagner
    Over the past two decades, there has been a remarkable surge in interest surrounding minitablets (MTs), particularly within the last ten years, as evidenced by the plethora of publications documented …
    a qbd approach

    Technical considerations for developing oral solids

    Newsfeeds - 24/10/2023 -
    Part 1 of the series by Pfizer CentreOne focuses on technical considerations for developing oral solids. The article emphasizes the significance of thorough technical groundwork and understanding excipients during the …
    System model driven selection of robust tablet manufacturing processes based on drug loading and formulation physical attributes

    System model driven selection of robust tablet manufacturing processes based on drug loading and formulation physical attributes

    Papers - 01/05/2022 - by Leah R. White, Matthew Molloy, Robert J. Shaw, Gavin K. Reynolds
    Utilizing mechanistic process modeling offers an opportunity to alleviate experimental demands, allowing for the establishment of relationships between process parameters and product attributes through in-silico experiments. A system model for …
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    The expanding role of effervescent technology

    Newsfeeds - 08/04/2022 -
    This article explains the benefits and applications of effervescent technology in solid dosage forms from beverages to laundry detergent.
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    Using a model-based material sparing approach for formulation and process development of a roller compacted drug product

    Papers - 26/02/2022 - by Kalyan V. Vasudevan, Yu Elaine Pu, Hossein Amini, Catherine Guarino, Anjali Agrawal, Ilgaz Akseli
    This study outlines an efficient approach that integrates material profiling, Instron uniaxial die-punch testing, and a mathematical model for roller compaction to guide the formulation and process development of a …
    A new validation methodology for in silico tools based on X-ray computed tomography images of tablets and a performance analysis of one tool

    A new validation methodology for in silico tools based on X-ray computed tomography images of tablets and a performance analysis of one tool

    Papers - 16/09/2021 - by Sebastian Bollmann, Peter Kleinebudde
    The validation of in silico tools predicting the dissolution of pharmaceutical dosage forms through virtual matrices can be accomplished using X-ray micro-computed tomography images of actual pharmaceutical formulations. In this …
    TPLS as predictive platform for twin-screw wet granulation process and formulation development

    TPLS as predictive platform for twin-screw wet granulation process and formulation development

    Papers - 08/06/2021 - by A. Ryckaert, D. Van Hauwermeiren, J. Dhondt, A. De Man, A. Funke, D. Djuric, C. Vervaet, I. Nopens, T. De Beer
    In recent years, there has been a growing interest in continuous manufacturing techniques, such as twin-screw wet granulation. However, our comprehension of how the combination of raw material properties and …
    Direct compression tablet formulation of Celecoxib enabled with a pharmaceutical solvate

    Direct compression tablet formulation of Celecoxib enabled with a pharmaceutical solvate

    Papers - 21/01/2021 - by Changquan Calvin Sun, Kunlin Wang
    Celecoxib, an anti-inflammatory medication used for pain and arthritis, is presently exclusively offered in capsule form. To expedite its onset time for quicker efficacy and reduce manufacturing expenses, the tablet …
    Evaluation of different pre-processing methods of X-ray micro computed tomography images

    Evaluation of different pre-processing methods of X-ray micro computed tomography images

    Papers - 03/12/2020 - by Sebastian Bollmann, Peter Kleinebudde
    The objective of this study was to assess the impact of various pre-processing methods on X-ray micro-computed tomography images of 12 distinct tablet batches, aiming to provide accurate images for …
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    In silico and in vitro methods to optimize the performance of experimental gastroretentive floating mini-tablets

    Papers - 03/05/2016 - by Veronika A. Eberle, Armella Häring, Joachim Schoelkopf, Patrick A. C. Gane, Jörg Huwyler, Maxim Puchkov
    Background: Developing floating drug delivery systems (FDDS) is a complex task. To simplify this process, a method was introduced for the simultaneous assessment of drug release and flotation. Objective: The …